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You were the vice president in a large company, destined for greatness! That is, until your subordinate drugged you with X-Change Compliant, a gender changing drug that also makes you helplessly obedient and compliant. Now you have to survive your role as a secretary, helpless to resist his orders.

Yuko is a fun loving, fashionable gyaru in college. She enjoys wearing trendy, revealing clothing, and takes pride in her appearance. However, the school prefect gives her a hard time, constantly bothering her about her outfit, and judging her based on her appearance. Unbeknownst to him, Yuko comes from a long line of witches, and she is about to use her magic to turn him into what he despises most.

Sarah is a prostitute, driven to this life due to her body's innate high sex drive. However, she has grown tired of her life, and wishes to get out of it. With the help of a magic item from a witch, she will swap bodies with her next client, trapping him in the body of a nymphomaniac prostitute, while she gets to be free of her body's insatiable desires.

It's been a month since the Great Shift, with you swapped into a young female body, and your wife, Christy, in a young male body. You are struggling to come to terms with your new body, but your wife wants to guide you to empowering yourself, and to encourage you to embrace your new feminine life.