Yes, the Wachowski brothers, who created the movie "The Matrix" and its sequels, have both transitioned and are now known as the Wachowski sisters.

Lana Wachowski, formerly known as Larry Wachowski, came out as a transgender woman in 2012 [2]. Lilly Wachowski, formerly known as Andy Wachowski, followed suit and also came out as a transgender woman in 2016 [3].

Together, Lana and Lilly Wachowski have had a successful career as American film and television directors, writers, and producers. They made their directing debut in 1996 with the film "Bound" and achieved fame with their second film, "The Matrix" (1999), which became a major box office success [2]. They went on to write and direct the sequels, "The Matrix Reloaded" and "The Matrix Revolutions" (both in 2003), and were involved in the writing and production of other works in the "Matrix" franchise [2].

Learn more:

1. Did the Wachowski brothers who created the movie ... - Quora
2. The Wachowskis - Wikipedia
3. Matrix directors Wachowski Brothers are now Wachowski Sisters. Yes, a sex change has happened! - India Today